Gut microbiota as a target in the bone health of livestock and poultry: roles of short-chain fatty acids

Abstract The regulation and maintenance of bone metabolic homeostasis are crucial for animal skeletal health. It has been established that structural alterations in the gut microbiota ecological dysbiosis closely associated with homeostasis. its metabolites, especially short-chain fatty acids (SCFAs), affect almost all organs, including bone. In this process, SCFAs positively healing by acting directly on cells involved repair after or shaping appropriate anti-inflammatory immunomodulatory responses. Additionally, have potential to maintain health livestock poultry because their various biological functions regulating metabolism, immune function, calcium absorption, osteogenesis osteolysis. This review primarily focuses role metabolism provides insight into studies related poultry.